Barbara Bottazzi Selected Research

Pattern Recognition Receptors

11/2022	The natural FGF-trap long pentraxin 3 inhibits lymphangiogenesis and lymphatic dissemination.
1/2021	Complementary Roles of Short and Long Pentraxins in the Complement-Mediated Immune Response to Aspergillus fumigatus Infections.
11/2014	Systemic pentraxin-3 levels reflect vascular enhancement and progression in Takayasu arteritis.
3/2009	Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation.
1/2008	Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3.
11/2006	The long pentraxin PTX3 in vascular pathology.
8/2006	Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3.
1/2006	Pentraxins in innate immunity and inflammation.
9/2005	Pentraxin 3 inhibits fibroblast growth factor 2-dependent activation of smooth muscle cells in vitro and neointima formation in vivo.
1/2005	Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

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Barbara Bottazzi Research Topics

Disease

48	Inflammation (Inflammations) 04/2024 - 02/2003
15	Infections 01/2023 - 03/2008
13	Neoplasms (Cancer) 01/2023 - 12/2006
12	COVID-19 04/2024 - 01/2021
7	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 05/2002
5	Sepsis (Septicemia) 01/2022 - 01/2017
4	Rheumatoid Arthritis 01/2021 - 09/2013
3	Fibrosis (Cirrhosis) 01/2021 - 09/2013
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2017 - 03/2010
3	Rheumatic Diseases (Rheumatism) 01/2017 - 03/2010
2	Post-Acute COVID-19 Syndrome 01/2023 - 11/2022
2	Shock 01/2022 - 01/2017
2	Septic Shock (Toxic Shock Syndrome) 11/2021 - 01/2017
2	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 01/2020
2	Wounds and Injuries (Trauma) 01/2021 - 01/2016
2	Takayasu Arteritis (Arteritis, Takayasu's) 03/2020 - 11/2014
2	Giant Cell Arteritis (Horton Disease) 03/2020 - 01/2016
2	Polycythemia Vera 01/2017 - 02/2011
2	Communicable Diseases (Infectious Diseases) 01/2017 - 01/2009
2	Essential Thrombocythemia 01/2017 - 02/2011
2	Thrombosis (Thrombus) 01/2017 - 02/2011
2	Pneumonia (Pneumonitis) 10/2014 - 01/2014
2	Acute-Phase Reaction 01/2012 - 04/2010
2	Myocardial Infarction 01/2012 - 07/2011
2	Human Influenza (Influenza) 10/2010 - 03/2008
2	Fibrosarcoma 12/2006 - 03/2006
1	Acute Disease 04/2024
1	Familial cerebral cavernous malformation 12/2023
1	Thyroid Diseases (Thyroid Disease) 01/2023
1	Thyroid Neoplasms (Thyroid Cancer) 01/2023
1	Carcinogenesis 01/2023
1	Lung Neoplasms (Lung Cancer) 01/2023
1	Osteoarthritis 01/2023
1	Parkinson Disease (Parkinson's Disease) 01/2023
1	Melanoma (Melanoma, Malignant) 11/2022
1	Pancreatic Neoplasms (Pancreatic Cancer) 05/2022
1	Osteomyelitis 01/2022
1	Coinfection 11/2021
1	Brain Injuries (Brain Injury) 10/2021
1	Craniocerebral Trauma (Head Injury) 10/2021

Drug/Important Bio-Agent (IBA)

33	PTX3 proteinIBA 04/2024 - 02/2003
21	Biomarkers (Surrogate Marker)IBA 04/2024 - 03/2010
19	Complement System Proteins (Complement)IBA 04/2024 - 01/2010
11	Pattern Recognition ReceptorsIBA 11/2022 - 07/2004
10	C-Reactive ProteinIBA 01/2023 - 05/2002
10	Proteins (Proteins, Gene)FDA Link 05/2022 - 05/2002
7	CytokinesIBA 01/2022 - 12/2006
6	Antiviral Agents (Antivirals)IBA 01/2023 - 03/2008
5	AntibodiesIBA 01/2023 - 04/2010
5	Acute-Phase Proteins (Acute-Phase Protein)IBA 04/2020 - 02/2003
3	ChemokinesIBA 01/2023 - 03/2006
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 11/2022 - 07/2004
3	Interleukin-8 (Interleukin 8)IBA 01/2022 - 01/2021
2	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2021
2	Immunologic Factors (Immunomodulators)IBA 01/2023 - 11/2022
2	LigandsIBA 01/2023 - 01/2011
2	InterferonsIBA 01/2023 - 11/2022
2	P-SelectinIBA 01/2023 - 04/2010
2	Monoclonal AntibodiesIBA 01/2023 - 11/2022
2	AutoantibodiesIBA 01/2023 - 01/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2022 - 03/2020
2	Interleukin-10 (Interleukin 10)IBA 01/2022 - 12/2006
2	AlbuminsIBA 11/2021 - 01/2017
2	Immunoglobulin G (IgG)IBA 11/2021 - 01/2020
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 10/2021 - 09/2005
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021 - 12/2016
2	siltuximabIBA 09/2021 - 01/2021
2	VaccinesIBA 12/2019 - 01/2017
2	Amyloid (Amyloid Fibrils)IBA 01/2016 - 01/2009
2	Interleukin-1 (Interleukin 1)IBA 01/2013 - 06/2003
2	NF-kappa B (NF-kB)IBA 12/2006 - 03/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2023
1	Glycoproteins (Glycoprotein)IBA 11/2023
1	Interleukin-1 Type II ReceptorsIBA 01/2023
1	tryptamineIBA 01/2023
1	CarcinogensIBA 01/2023
1	Small Cytoplasmic RNAIBA 01/2023
1	Chemokine ReceptorsIBA 01/2023
1	NAD (NADH)IBA 01/2023
1	Tryptophan (L-Tryptophan)FDA Link 01/2023
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 11/2022
1	Conditioned Culture MediaIBA 11/2022
1	Vascular Endothelial Growth Factor CIBA 11/2022
1	Vascular Endothelial Growth FactorsIBA 11/2022
1	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2022
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2022
1	Interleukin-18 (Interleukin 18)IBA 01/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Intravenous Immunoglobulins (IVIG)FDA Link 11/2021
1	Immunoglobulin M (IgM)IBA 11/2021
1	Immunoglobulin A (IgA)IBA 11/2021
1	Glial Fibrillary Acidic ProteinIBA 10/2021
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 10/2021

Therapy/Procedure

4	Therapeutics 01/2019 - 09/2013
2	Resuscitation 01/2017 - 10/2015
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2017 - 09/2013
1	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2023
1	Arthroplasty 01/2023
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2023
1	Critical Care (Surgical Intensive Care) 10/2021